Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature02835.pdf
Reference30 articles.
1. Gurdon, J. B. & Bourillot, P. Y. Morphogen gradient interpretation. Nature 413, 797–803 (2001)
2. Ingham, P. W., Taylor, A. M. & Nakano, Y. Role of the Drosophila patched gene in positional signalling. Nature 353, 184–187 (1991)
3. Chen, Y. & Struhl, G. Dual roles for patched in sequestering and transducing Hedgehog. Cell 87, 553–563 (1996)
4. Stone, D. M. et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384, 129–134 (1996)
5. Marigo, V., Davey, R. A., Zuo, Y., Cunningham, J. M. & Tabin, C. J. Biochemical evidence that patched is the Hedgehog receptor. Nature 384, 176–179 (1996)
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