The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4-Reference-Cited by-同舟云学术

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

Published:2004-03 Issue:6980 Volume:428 Page:341-345
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Hsu Li-Chung,Mo Park Jin,Zhang Kezhong,Luo Jun-Li,Maeda Shin,Kaufman Randal J.,Eckmann Lars,Guiney Donald G.,Karin Michael

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature02405.pdf

Reference30 articles.

1. Aderem, A. & Ulevitch, R. J. Toll-like receptors in the induction of the innate immune response. Nature 406, 782–787 (2000)

2. Medzhitov, R. Toll-like receptors and innate immunity. Nature Rev. Immunol. 1, 135–145 (2001)

3. Weinrauch, Y. & Zychlinsky, A. The induction of apoptosis by bacterial pathogens. Annu. Rev. Microbiol. 53, 155–187 (1999)

4. Park, J. M., Greten, F. R., Li, Z. W. & Karin, M. Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297, 2048–2051 (2002)

5. Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085–2088 (1998)

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