Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway-Reference-Cited by-同舟云学术

Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway

Published:2016-12 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Hui Xian,Yue Qiao,Zhang Dan-Dan,Li Heng,Yang Shao-Qing,Gao Wen-Yun

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep38945.pdf

Reference30 articles.

1. Rohmer, M. In Comprehensive Natural Products II: Chemistry and Biology (eds Mander, L. & Liu, H. W. ) 517–556 (Oxford, 2010).

2. Singh, N., Cheve, G., Avery, M. A. & McCurdy, C. R. Targeting the MEP pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of DXR enzyme. Curr. Pharm. Design 13, 1161–1177 (2007).

3. Jomaa, H. et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science 285, 1573–1576 (1999).

4. Missinou, M. A. et al. Fosmidomycin for malaria. Lancet 360, 1941–1942 (2002).

5. Kaiser, J. et al. Anti-malarial drug targets: Screening for inhibitors of IspC protein in Mediterranean plants. Phytomedicine 14, 242–249 (2007).

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