Therapeutic antibody targeting of individual Notch receptors-Reference-Cited by-同舟云学术

Therapeutic antibody targeting of individual Notch receptors

Published:2010-04 Issue:7291 Volume:464 Page:1052-1057
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Wu Yan,Cain-Hom Carol,Choy Lisa,Hagenbeek Thijs J.,de Leon Gladys P.,Chen Yongmei,Finkle David,Venook Rayna,Wu Xiumin,Ridgway John,Schahin-Reed Dorreyah,Dow Graham J.,Shelton Amy,Stawicki Scott,Watts Ryan J.,Zhang Jeff,Choy Robert,Howard Peter,Kadyk Lisa,Yan Minhong,Zha Jiping,Callahan Christopher A.,Hymowitz Sarah G.,Siebel Christian W.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature08878.pdf

Reference38 articles.

1. Aster, J. C., Pear, W. S. & Blacklow, S. C. Notch signaling in leukemia. Annu. Rev. Path. 3, 587–613 (2008)

2. Kopan, R. & Ilagan, M. X. G. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216–233 (2009)

3. Mumm, J. S. et al. A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1. Mol. Cell 5, 197–206 (2000)

4. Brou, C. et al. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol. Cell 5, 207–216 (2000)

5. Gordon, W. R. et al. Structural basis for autoinhibition of Notch. Nature Struct. Mol. Biol. 14, 295–300 (2007)

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