Interferons induce tyrosine phosphorylation of the eIF2α kinase PKR through activation of Jak1 and Tyk2-Reference-Cited by-同舟云学术

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Interferons induce tyrosine phosphorylation of the eIF2α kinase PKR through activation of Jak1 and Tyk2

Published:2007-02-09 Issue:3 Volume:8 Page:265-270
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Rep

Author:

Su Qiaozhu¹,Wang Shuo¹,Baltzis Dionissios¹,Qu Li‐Ke¹,Raven Jennifer F¹,Li Suiyang¹,Wong Andrew Hoi‐Tao¹,Koromilas Antonis E¹

Affiliation:

1. Lady Davis Institute, Sir Mortimer B. Davis‐Jewish General Hospital 3999 Cote Ste‐Catherine Road Montreal Quebec H3T 1E2 Canada

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1038/sj.embor.7400891

Reference34 articles.

1. Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR

2. Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3

3. Initiation Factor eIF2α Phosphorylation in Stress Responses and Apoptosis

4. Gene-Specific Regulation by General Translation Factors

5. Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

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