Detecting cAMP‐induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

Author:

Ponsioen Bas12,Zhao Jun3,Riedl Jurgen3,Zwartkruis Fried3,van der Krogt Gerard1,Zaccolo Manuela4,Moolenaar Wouter H2,Bos Johannes L3,Jalink Kees1

Affiliation:

1. Division of Cell Biology, The Netherlands Cancer Institute Plesmanlaan 121 1066CX Amsterdam The Netherlands

2. Division of Cellular Biochemistry and Centre of Biomedical Genetics, The Netherlands Cancer Institute Plesmanlaan 121 1066CX Amsterdam The Netherlands

3. Department of Physiological Chemistry and Centre of Biomedical Genetics, UMCU Universiteitsweg 100 3584 CG Utrecht The Netherlands

4. Dulbecco Telethon Institute, Venetian Institute of Molecular Medicine Via Orus 2 35124 Padva Padova Italy

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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