Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad∆∆ through Bcl-2-dependent attenuation of autophagy-Reference-Cited by-同舟云学术

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Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad∆∆ through Bcl-2-dependent attenuation of autophagy

Published:2018-01 Issue:1 Volume:7 Page:
ISSN:2157-9024
Container-title:Oncogenesis
language:en
Short-container-title:Oncogenesis

Author:

Aguirre-Hernández Carmen,Maya-Pineda Héctor,Millán Julia San,Man Y. K. Stella,Lu Yong-Jie,Halldén Gunnel

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology

Link

http://www.nature.com/articles/s41389-017-0020-8.pdf

Reference49 articles.

1. Freytag, S. O. et al. Prospective randomized phase 2 trial of intensity modulated radiation therapy with or without oncolytic adenovirus-mediated cytotoxic gene therapy in intermediate-risk prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 89, 268–276 (2014).

2. Small, E. J. et al. A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer. Mol. Ther. 14, 107–117 (2006).

3. Botta, G. et al. Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo. Hum. Gene. Ther. 23, 623–634 (2012).

4. Radhakrishnan, S. et al. Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts. Hum. Gene. Ther. 21, 1311–1325 (2010).

5. Raki, M. et al. Oncolytic adenovirus Ad5/3-delta24 and chemotherapy for treatment of orthotopic ovarian cancer. Gynecol. Oncol. 108, 166–172 (2008).

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1. Mitoxantrone ameliorates ineffective erythropoiesis in a β-thalassemia intermedia mouse model;Blood Advances;2024-07-29

2. Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response;Frontiers in Cellular and Infection Microbiology;2023-03-15

3. Current Views on Oncolytic Adenoviruses for Cancer Therapy;Current Cancer Therapy Reviews;2022-11

4. Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells;Archives of Toxicology;2022-10-10

5. Complexing the Oncolytic Adenoviruses Ad∆∆ and Ad-3∆-A20T with Cationic Nanoparticles Enhances Viral Infection and Spread in Prostate and Pancreatic Cancer Models;International Journal of Molecular Sciences;2022-08-10

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