Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability

Author:

Bokhari A’dem,Jonchere Vincent,Lagrange Anaïs,Bertrand Romane,Svrcek Magali,Marisa LaetitiaORCID,Buhard Olivier,Greene Malorie,Demidova Anastasia,Jia Jieshuang,Adriaenssens Eric,Chassat Thierry,Biard Denis S.,Flejou Jean-François,Lejeune Fabrice,Duval Alex,Collura AdaORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology

Reference46 articles.

1. Larrea, A. A., Lujan, S. A. & Kunkel, T. A. SnapShot: DNA mismatch repair. Cell 141, 730e1 (2010).

2. Duval, A. & Hamelin, R. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res. 62, 2447–2454 (2002).

3. Hause, R. J., Pritchard, C. C., Shendure, J. & Salipante, S. J. Classification and characterization of microsatellite instability across 18 cancer types. Nat. Med. 22, 1342–1350 (2016).

4. Liu, W. et al. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat. Genet. 26, 146–147 (2000).

5. Duval, A. et al. The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines. Cancer Res. 60, 3872–3879 (2000).

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