Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia-Reference-Cited by-同舟云学术

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Published:2015-09-21 Issue:10 Volume:21 Page:1182-1189
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Herranz Daniel,Ambesi-Impiombato Alberto,Sudderth Jessica,Sánchez-Martín Marta,Belver Laura,Tosello Valeria,Xu Luyao,Wendorff Agnieszka A,Castillo Mireia,Haydu J Erika,Márquez Javier,Matés José M^ORCID,Kung Andrew L,Rayport Stephen^ORCID,Cordon-Cardo Carlos^ORCID,DeBerardinis Ralph J,Ferrando Adolfo A

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3955.pdf

Reference34 articles.

1. Hori, K., Sen, A. & Artavanis-Tsakonas, S. Notch signaling at a glance. J. Cell Sci. 126, 2135–2140 (2013).

2. Rothenberg, E.V., Moore, J.E. & Yui, M.A. Launching the T-cell-lineage developmental programme. Nat. Rev. Immunol. 8, 9–21 (2008).

3. Thompson, P.K. & Zuniga-Pflucker, J.C. On becoming a T cell, a convergence of factors kick it up a Notch along the way. Semin. Immunol. 23, 350–359 (2011).

4. Ciofani, M. & Zuniga-Pflucker, J.C. Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. Nat. Immunol. 6, 881–888 (2005).

5. Weng, A.P. et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306, 269–271 (2004).

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