Ultra-sensitive detection of tumorigenic cellular impurities in human cell-processed therapeutic products by digital analysis of soft agar colony formation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep17892.pdf
Reference31 articles.
1. Tanna, T. & Sachan, V. Mesenchymal stem cells: potential in treatment of neurodegenerative diseases. Curr. Stem Cell Res. Ther. 9, 513–521 (2014).
2. Wei, X. et al. Mesenchymal stem cells: a new trend for cell therapy. Acta. Pharmacol. Sin. 34, 747–754 (2013).
3. Barkholt, L. et al. Risk of tumorigenicity in mesenchymal stromal cell-based therapies–bridging scientific observations and regulatory viewpoints. Cytotherapy 15, 753–759 (2013).
4. Meier, R. P., Muller, Y. D., Morel, P., Gonelle-Gispert, C. & Buhler, L. H. Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence ? Stem Cell Res. 11, 1348–1364 (2013).
5. Rosland, G. V. et al. Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation. Cancer Res. 69, 5331–5339 (2009).
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