EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis-Reference-Cited by-同舟云学术

EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis

Published:2018-07-16 Issue:11 Volume:39 Page:1777-1786
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Liu Wen-Juan,Liu Xiu-Jun,Xu Jian,Li Liang,Li Yi,Zhang Sheng-Hua,Wang Jia-Lin,Miao Qing-Fang,Zhen Yong-Su

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-018-0069-8.pdf

Reference29 articles.

1. Jarczak J, Kosciuczuk EM, Lisowski P, Strzalkowska N, Jozwik A, Horbanczuk J, et al. Defensins: natural component of human innate immunity. Hum Immunol. 2013;74:1069–79.

2. Suarez-Carmona M, Hubert P, Delvenne P, Herfs M. Defensins: “Simple” antimicrobial peptides or broad-spectrum molecules? Cytokine Growth Factor Rev. 2015;26:361–70.

3. Ulm H, Wilmes M, Shai Y, Sahl HG. Antimicrobial host defensins-specific antibiotic activities and innate defense modulation. Front Immunol. 2012;3:249

4. Cederlund A, Gudmundsson GH, Agerberth B. Antimicrobial peptides important in innate immunity. FEBS J. 2011;278:3942–51.

5. Du Y, Shang BY, Sheng WJ, Zhang SH, Li Y, Miao QF, et al. A recombinantly tailored beta-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer. Oncotarget. 2016;7:58418–34.

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human β-defensins and their synthetic analogs: Natural defenders and prospective new drugs of oral health;Life Sciences;2024-06

2. Mechanisms and regulation of defensins in host defense;Signal Transduction and Targeted Therapy;2023-08-14

3. Tuftsin-tailored fusion protein inhibits the growth of circulating gastric tumor cells associated with macrophage phagocytosis;Biochemistry and Biophysics Reports;2023-07

4. Association between α‐defensin 5 and the expression and function of P‐glycoprotein in differentiated intestinal Caco‐2 cells;Biopharmaceutics & Drug Disposition;2023-06-05

5. Sulfonylated Indeno[1,2-c]quinoline Derivatives as Potent EGFR Tyrosine Kinase Inhibitors;ACS Omega;2023-05-23