EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells-Reference-Cited by-同舟云学术

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EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells

Published:2019-07-17 Issue:2 Volume:41 Page:270-277
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Chen Yue-hong,Lv Hao,Shen Ning,Wang Xiao-min,Tang Shuai,Xiong Bing,Ding Jian,Geng Mei-yu,Huang Min

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-019-0268-y.pdf

Reference23 articles.

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2. Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ. Drugging the undruggable RAS: mission possible? Nat Rev Drug Discov. 2014;13:828–51.

3. Papke B, Der CJ. Drugging RAS: know the enemy. Science. 2017;355:1158–63.

4. Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nat Rev Mol Cell Biol. 2008;9:517–31.

5. Fehrenbacher N, Bar-Sagi D, Philips M. Ras/MAPK signaling from endomembranes. Mol Oncol. 2009;3:297–307.

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