Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors-Reference-Cited by-同舟云学术

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Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors

Published:2021-01-25 Issue:7 Volume:42 Page:1160-1170
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Chen Xiao-bing,Zhu Hai-ying,Bao Kun,Jiang Li,Zhu Hong,Ying Mei-dan,He Qiao-jun,Yang Bo,Sheng Rong,Cao Ji

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-020-00600-5.pdf

Reference52 articles.

1. Nagakubo D, Taira T, Kitaura H, Ikeda M, Tamai K, Iguchi-Ariga SM, et al. DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun. 1997;231:509–13.

2. Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. 2003;299:256–9.

3. Aleyasin H, Rousseaux MW, Phillips M, Kim RH, Bland RJ, Callaghan S, et al. The Parkinson’s disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Natl Acad Sci USA. 2007;104:18748–53.

4. Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, et al. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. J Biol Chem. 2006;281:10816–24.

5. Sajjad MU, Green EW, Miller-Fleming L, Hands S, Herrera F, Campesan S, et al. DJ-1 modulates aggregation and pathogenesis in models of Huntington’s disease. Hum Mol Genet. 2014;23:755–66.

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1. The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA;Journal of Biological Chemistry;2024-07

2. Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell;Journal of Medicinal Chemistry;2024-05-07

3. Discovery of Novel Covalent Inhibitors of DJ-1 Through Hybrid Virtual Screening;Future Medicinal Chemistry;2024-03-22

4. Synthesis, biological activity evaluation and mechanism of action of novel bis-isatin derivatives as potential anti-liver cancer agents;Bioorganic & Medicinal Chemistry Letters;2024-02

5. Biologically active symmetric and asymmetric dicationic <i>bis</i>-isatinhydrazones: which is better - complicing or simplifying the structure of the spacer?;Журнал органической химии;2023-12-15

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