Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain-Reference-Cited by-同舟云学术

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Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain

Published:2021-12-14 Issue: Volume: Page:
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Li Teng-teng,Peng Cheng,Wang Ji-qiu,Xu Zhi-jian,Su Ming-bo,Li Jia,Zhu Wei-liang,Li Jing-ya

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-021-00818-x.pdf

Reference45 articles.

1. Rohrborn D, Wronkowitz N, Eckel J. DPP4 in diabetes. Front Immunol. 2015;6:386.

2. Zhong J, Maiseyeu A, Davis SN, Rajagopalan S. DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. Circ Res. 2015;116:1491–504.

3. Gorrell MD. Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin Sci. 2005;108:277–92.

4. Deacon CF. Physiology and pharmacology of DPP-4 in glucose homeostasis and the treatment of type 2 diabetes. Front Endocrinol. 2019;10:80.

5. Gorrell MD, Gysbers V, McCaughan GW. CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes. Scand J Immunol. 2001;54:249-64.

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