Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening-Reference-Cited by-同舟云学术

Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening

Published:2019-06-28 Issue:2 Volume:41 Page:286-292
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Zhang Feng-cai,Sun Zhong-ya,Liao Li-ping,Zuo Yu,Zhang Dan,Wang Jun,Chen Yan-tao,Xiao Sen-hao,Jiang Hao,Lu Tian,Xu Pan,Yue Li-yan,Du Dao-hai,Zhang Hao,Liu Chuan-peng,Luo Cheng

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-019-0256-2.pdf

Reference36 articles.

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2. Raisner R, Kharbanda S, Jin L, Jeng E, Chan E, Merchant M, et al. Enhancer activity requires CBP/P300 bromodomain-dependent histone H3K27 acetylation. Cell Rep. 2018;24:1722–9.

3. Das C, Roy S, Namjoshi S, Malarkey CS, Jones DNM, Kutateladze TG, et al. Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation. Proc Natl Acad Sci U S A. 2014;111:E1072–81.

4. Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Scholz C, et al. Time-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome. Cell. 2018;174:231–44 e12.

5. Iyer NG, Ozdag H, Caldas C. P300/CBP and cancer. Oncogene. 2004;23:4225–31.

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