TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis-Reference-Cited by-同舟云学术

TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis

Published:2023-03-30 Issue:8 Volume:44 Page:1649-1664
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Yang Wen-ji,Han Fang-hui,Gu Yi-pei,Qu Hui,Liu Jia,Shen Jian-hua,Leng Ying

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-023-01081-y.pdf

Reference50 articles.

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2. Gao C, Zhou Y, Chen Z, Li H, Xiao Y, Hao W, et al. Turmeric-derived nanovesicles as novel nanobiologics for targeted therapy of ulcerative colitis. Theranostics. 2022;12:5596–614.

3. Zhao J, Lin Z, Ying P, Zhao Z, Yang H, Qian J, et al. circSMAD4 promotes experimental colitis and impairs intestinal barrier functions by targeting JAK2 through sponging miR-135a-5p. J Crohns Colitis. 2022;jjac154. https://doi.org/10.1093/ecco-jcc/jjac154.

4. Scalavino V, Piccinno E, Bianco G, Schena N, Armentano R, Giannelli G, et al. The increase of miR-195-5p reduces intestinal permeability in ulcerative colitis, modulating tight junctions’ expression. Int J Mol Sci. 2022;23:5840.

5. Li X, Li Q, Xiong B, Chen H, Wang X, Zhang D. Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in ulcerative colitis through tight junction proteins degradation and epithelium apoptosis. Pharmacol Res. 2022;183:106368.

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