High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4-Reference-Cited by-同舟云学术

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High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4

Published:2020-03-31 Issue:10 Volume:41 Page:1328-1336
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Lin Guang-yao,Lin Lin,Cai Xiao-qing,Dai An-tao,Zhu Yue,Li Jie,Liu Qing,Yang De-hua,Bathgate Ross A. D.,Wang Ming-wei

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-020-0390-x.pdf

Reference26 articles.

1. Liu C, Kuei C, Sutton S, Chen J, Bonaventure P, Wu J, et al. INSL5 is a high affinity specific agonist for GPCR142 (GPR100). J Biol Chem. 2005;280:292–300.

2. Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol. 2003;63:1256–72.

3. Boels K, Schaller HC. Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor. Br J Pharmacol. 2003;140:932–8.

4. Kong RC, Shilling PJ, Lobb DK, Gooley PR, Bathgate RA. Membrane receptors: structure and function of the relaxin family peptide receptors. Mol Cell Endocrinol. 2010;320:1–15.

5. Akhter Hossain M, Bathgate RA, Kong CK, Shabanpoor F, Zhang S, Haugaard-Jonsson LM, et al. Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5). ChemBioChem. 2008;9:1816–22.

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1. Dihydroazolopyrimidines: Past, Present and Perspectives in Synthesis, Green Chemistry and Drug Discovery;The Chemical Record;2023-09-05

2. Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4);Nature Communications;2023-01-30

3. A unique peptide recognition mechanism by the human relaxin family peptide receptor 4 (RXFP4);2022-07-28

4. High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist;Molecules;2021-12-11

5. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors;British Journal of Pharmacology;2021-09-16

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