Small molecule compound M12 reduces vascular permeability in obese mice via blocking endothelial TRPV4–Nox2 interaction-Reference-Cited by-同舟云学术

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Small molecule compound M12 reduces vascular permeability in obese mice via blocking endothelial TRPV4–Nox2 interaction

Published:2021-10-15 Issue: Volume: Page:
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Gao Meng-ru,Zhang Peng,Han Jing,Tang Chun-lei,Zhu Yi-fei,Kan Hao,Li Hong-juan,Han Xi-ping,Ma Xin

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-021-00780-8.pdf

Reference48 articles.

1. Mundi S, Massaro M, Scoditti E, Carluccio MA, van Hinsbergh VWM, Iruela-Arispe ML, et al. Endothelial permeability, LDL deposition, and cardiovascular risk factors. Cardiovasc Res. 2018;114:35–52.

2. Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546–51.

3. Xu L, Nagata N, Ota T. Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. Adipocyte. 2018;7:218–25.

4. Filosa JA, Yao X, Rath G. TRPV4 and the regulation of vascular tone. J Cardiovasc Pharmacol. 2013;61:113–9.

5. Wu QF, Qian C, Zhao N, Dong Q, Li J, Wang BB, et al. Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes. Cell Death Dis. 2017;8:e2828.

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