DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis-Reference-Cited by-同舟云学术

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DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis

Published:2020-07-31 Issue:2 Volume:42 Page:264-271
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Huang Jun-shang,Guo Bin-bin,Wang Gai-hong,Zeng Li-min,Hu You-hong,Wang Ting,Wang He-yao

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/s41401-020-0482-7.pdf

Reference45 articles.

1. Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia. 2003;46:3–19.

2. Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives. Nat Rev Endocrinol. 2011;8:228–36.

3. Moffitt JH, Fielding BA, Evershed R, Berstan R, Currie JM, Clark A. Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro. Diabetologia. 2005;48:1819–29.

4. Poitout V, Robertson RP. Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr Rev. 2008;29:351–66.

5. Unger RH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications. Diabetes. 1995;44:863–70.

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