ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome-Reference-Cited by-同舟云学术

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ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome

Published:2021-08-02 Issue: Volume: Page:
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Wu Xiao-yan,Lv Jin-yan,Zhang Shi-qing,Yi Xin,Xu Zi-wei,Zhi Yuan-xing,Zhao Bo-xin,Pang Jian-xin,Yung Ken Kin Lam,Liu Shu-wen,Zhou Ping-zheng

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-021-00739-9.pdf

Reference56 articles.

1. Broz P, Dixit VM. Inflammasomes: mechanism of assembly, regulation and signalling. Nat Rev Immunol. 2016;16:407–20.

2. Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140:821–32.

3. Heneka MT, McManus RM, Latz E. Inflammasome signalling in brain function and neurodegenerative disease. Nat Rev Neurosci. 2018;19:610–21.

4. de Zoete MR, Palm NW, Zhu S, Flavell RA. Inflammasomes. Cold Spring Harb Perspect Biol. 2014;6:a016287.

5. Swanson KV, Deng M, Ting JP. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nat Rev Immunol. 2019;19:477–89.

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ML335 inhibits TWIK2 channel-mediated potassium efflux and attenuates mitochondrial damage in MSU crystal-induced inflammation;Journal of Translational Medicine;2024-08-22

2. ML365 ameliorates postoperative cognitive impairment in aged mice by inhibiting NLRP3 inflammasome activation in the hippocampus;Brain Research;2024-08

3. Extracellular histones promote TWIK2-dependent potassium efflux and associated NLRP3 activation in alveolar macrophages during sepsis-induced lung injury;Inflammation Research;2024-05-11

4. Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses;Nature Chemical Biology;2024-02-14

5. The role of inflammasomes in human diseases and their potential as therapeutic targets;Signal Transduction and Targeted Therapy;2024-01-05

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