Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel-Reference-Cited by-同舟云学术

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Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel

Published:2023-05-04 Issue:9 Volume:44 Page:1768-1776
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Wang Qiao-qiao,Wang Long,Zhang Wen-bo,Tang Chun-ping,Chen Xue-qin,Zheng Yue-ming,Yao Sheng,Gao Zhao-bing,Ye Yang

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

https://www.nature.com/articles/s41401-023-01084-9.pdf

Reference37 articles.

1. Catterall WA. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron. 2000;26:13–25.

2. Melnikova DI, Khotimchenko YS, Magarlamov TY. Addressing the issue of tetrodotoxin targeting. Mar Drugs. 2018;16:1053–61.

3. Djouhri L, Newton R, Levinson SR, Berry CM, Carruthers B, Lawson SN. Sensory and electrophysiological properties of guinea-pig sensory neurones expressing Nav1.7 (PN1) Na+ channel alpha subunit protein. J Physiol. 2003;546:565–76.

4. Bosmans F, Swartz KJ. Targeting voltage sensors in sodium channels with spider toxins. Trends Pharmacol Sci. 2010;31:175–82.

5. Vetter I, Deuis JR, Mueller A, Israel MR, Starobova H, Zhang A, et al. NaV1.7 as a pain target—from gene to pharmacology. Pharmacol Ther. 2017;172:73–100.

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1. A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels;Journal of Ethnopharmacology;2024-08

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