Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity-Reference-Cited by-同舟云学术

Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity

Published:2017-04-11 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Zhao Xinbin,Sun Kun,Lan Zhou,Song Wenxin,Cheng Lili,Chi Wenna,Chen Jing,Huo Yi,Xu Lina,Liu Xiaohui,Deng Haiteng,Siegenthaler Julie A.,Chen Ligong

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep46344.pdf

Reference50 articles.

1. Abdool Karim, Q. et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 329, 1168–1174 (2010).

2. Cui, G. Y., Xu, X. J. & Diao, H. Y. Comparative Meta-analysis of tenofovir disoproxil fumarate versus emtricitabine and tenofovir disoproxil fumarate as treatments for patients with chronic hepatitis B. Scientific Reports 5, 11854 (2015).

3. Dauchy, F. A. et al. Increased risk of abnormal proximal renal tubular function with HIV infection and antiretroviral therapy. Kidney International 80, 302–309 (2011).

4. Ramamoorthy, H., Abraham, P. & Isaac, B. Mitochondrial dysfunction and electron transport chain complex defect in a rat model of tenofovir disoproxil fumarate nephrotoxicity. Journal of Biochemical and Molecular Toxicology 28, 246–255 (2014).

5. Hall, A. M. Update on tenofovir toxicity in the kidney. Pediatric Nephrology 28, 1011–1023 (2013).

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Long‐term persistence of mitochondrial dysfunctions after viral infections and antiviral therapies: A review of mechanisms involved;Journal of Medical Virology;2024-09

2. Pyruvate dehydrogenase is a potential mitochondrial off-target for gentamicin based on in silico predictions and in vitro inhibition studies;Toxicology in Vitro;2024-03

3. MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation;Nature Communications;2024-01-02

4. Current drugs for HIV-1: from challenges to potential in HIV/AIDS;Frontiers in Pharmacology;2023-10-26

5. Human immunodeficiency virus and antiretroviral therapy-mediated immune cell metabolic dysregulation in children born to HIV-infected women: potential clinical implications;Frontiers in Immunology;2023-06-07