Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor-Reference-Cited by-同舟云学术

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Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

Published:2006-04-09 Issue:5 Volume:12 Page:580-584
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Baral Toya Nath,Magez Stefan,Stijlemans Benoît,Conrath Katja,Vanhollebeke Benoit,Pays Etienne,Muyldermans Serge,De Baetselier Patrick

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1395.pdf

Reference30 articles.

1. Vanhamme, L. et al. Apolipoprotein L–I is the trypanosome lytic factor of human serum. Nature 422, 83–87 (2003).

2. Xong, H.V. et al. A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense. Cell 95, 839–846 (1998).

3. Stijlemans, B. et al. Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm. J. Biol. Chem. 279, 1256–1261 (2004).

4. Hutchinson, O.C., Fevre, E.M., Carrington, M. & Welburn, S.C. Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda. Lancet Infect. Dis. 3, 42–45 (2003).

5. Barrett, M.P. et al. The trypanosomiases. Lancet 362, 1469–1480 (2003).

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