Translation of neutrally evolving peptides provides a basis for de novo gene evolution

Author:

Ruiz-Orera JorgeORCID,Verdaguer-Grau Pol,Villanueva-Cañas José LuisORCID,Messeguer Xavier,Albà M. MarORCID

Publisher

Springer Science and Business Media LLC

Subject

Ecology,Ecology, Evolution, Behavior and Systematics

Reference60 articles.

1. Kutter, C. et al. Rapid turnover of long noncoding RNAs and the evolution of gene expression. PLoS Genet. 8, e1002841 (2012).

2. Wiberg, R. A. W. et al. Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome. Genome Biol. Evol. 7, 2432–2444 (2015).

3. Ruiz-Orera, J. et al. Origins of de novo genes in human and chimpanzee. PLoS Genet. 11, e1005721 (2015).

4. Ji, Z., Song, R., Regev, A. & Struhl, K. Many lncRNAs, 5'UTRs, and pseudogenes are translated and some are likely to express functional proteins. Elife 4, e08890 (2015).

5. Raj, A. et al. Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling. Elife 5, e13328 (2016).

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