Author:
Lee Cheng-Ruei,Wang Baosheng,Mojica Julius P.,Mandáková Terezie,Prasad Kasavajhala V. S. K.,Goicoechea Jose Luis,Perera Nadeesha,Hellsten Uffe,Hundley Hope N.,Johnson Jenifer,Grimwood Jane,Barry Kerrie,Fairclough Stephen,Jenkins Jerry W.,Yu Yeisoo,Kudrna Dave,Zhang Jianwei,Talag Jayson,Golser Wolfgang,Ghattas Kathryn,Schranz M. Eric,Wing Rod,Lysak Martin A.,Schmutz Jeremy,Rokhsar Daniel S.,Mitchell-Olds Thomas
Abstract
Abstract
Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favoured alleles at multiple loci. However, it is unknown whether favoured mutations slowly accumulate on older inversions or if young inversions spread because they capture pre-existing adaptive quantitative trait loci (QTLs). By genetic mapping, chromosome painting and genome sequencing, we have identified a major inversion controlling ecologically important traits in Boechera stricta. The inversion arose since the last glaciation and subsequently reached local high frequency in a hybrid speciation zone. Furthermore, the inversion shows signs of positive directional selection. To test whether the inversion could have captured existing, linked QTLs, we crossed standard, collinear haplotypes from the hybrid zone and found multiple linked phenology QTLs within the inversion region. These findings provide the first direct evidence that linked, locally adapted QTLs may be captured by young inversions during incipient speciation.
Publisher
Springer Science and Business Media LLC
Subject
Ecology,Ecology, Evolution, Behavior and Systematics
Cited by
107 articles.
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