Total synthesis of brevetoxin A
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/32623.pdf
Reference45 articles.
1. Shimizu, Y., Chou, H.-N. & Bando, H. Structure of brevetoxin A (GB-1 toxin), the most potent toxin in the Florida red tide organism Gymnodinium breve (Ptychodiscus brevis). J. Am. Chem. Soc. 108, 514–515 (1986).
2. Shimizu, Y., Bando, H., Chou, H.-N., Van Duyne, G. & Clardy, J. C. Absolute configuration of brevetoxins. J. Chem. Soc., Chem. Commun. 1656–1658 (1986).
3. Pawlak, J.et al. Structure of brevetoxin A as constructed from NMR and MS data. J. Am. Chem. Soc. 109, 1144–1150 (1987).
4. Rein, K. S., Baden, D. G. & Gawley, R. E. Conformational analysis of the sodium channel modulator, brevetoxin A, comparison with brevetoxin B conformations, and a hypothesis about the common pharmacophore of the “site 5” toxins. J. Org. Chem. 59, 2101–2106 (1994).
5. Rein, K. S., Lynn, B., Baden, D. G. & Gawley, R. E. Brevetoxin B: chemical modifications, synaptosome binding, toxicity, and an unexpected conformational effect. J. Org. Chem. 59, 2107–21013 (1994).
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