Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK-Reference-Cited by-同舟云学术

Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK

Published:2017-02 Issue:5 Volume:116 Page:609-619
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Patel Girijesh Kumar,Khan Mohammad Aslam,Bhardwaj Arun,Srivastava Sanjeev K,Zubair Haseeb,Patton Mary C,Singh Seema,Khushman Moh'd,Singh Ajay P

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/bjc201718.pdf

Reference49 articles.

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3. Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP (2013) An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor kappaB- and hypoxia-inducible factor 1alpha-mediated up-regulation of CXCR4. J Biol Chem 288 (29): 21197–21207.

4. Azmi AS, Bao B, Sarkar FH (2013) Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Rev 32 (3-4): 623–642.

5. Bhardwaj A, Arora S, Prajapati VK, Singh S, Singh AP (2013) Cancer ‘stemness’- regulating microRNAs: role, mechanisms and therapeutic potential. Curr Drug Targets 14 (10): 1175–1184.

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