Screening out irrelevant cell-based models of disease-Reference-Cited by-同舟云学术

Screening out irrelevant cell-based models of disease

Published:2016-09-12 Issue:11 Volume:15 Page:751-769
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Horvath Peter,Aulner Nathalie,Bickle Marc,Davies Anthony M.,Nery Elaine Del,Ebner Daniel,Montoya Maria C.,Östling Päivi,Pietiäinen Vilja,Price Leo S.,Shorte Spencer L.,Turcatti Gerardo,von Schantz Carina,Carragher Neil O.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd.2016.175.pdf

Reference228 articles.

1. Waldmeier, P., Bozyczko-Coyne, D., Williams, M. & Vaught, J. L. Recent clinical failures in Parkinson's disease with apoptosis inhibitors underline the need for a paradigm shift in drug discovery for neurodegenerative diseases. Biochem. Pharmacol. 72, 1197–1206 (2006).

2. Bolognesi, M. L., Matera, R., Minarini, A., Rosini, M. & Melchiorre, C. Alzheimer's disease: new approaches to drug discovery. Curr. Opin. Chem. Biol. 13, 303–308 (2009).

3. Paul, S. M. et al. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nat. Rev. Drug Discov. 9, 203–214 (2010).

4. Mangialasche, F., Solomon, A., Winblad, B., Mecocci, P. & Kivipelto, M. Alzheimer's disease: clinical trials and drug development. Lancet Neurol. 9, 702–716 (2010).

5. Hoelder, S., Clarke, P. A. & Workman, P. Discovery of small molecule cancer drugs: successes, challenges and opportunities. Mol. Oncol. 6, 155–176 (2012).

Cited by 415 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Achieving high-resolution single-cell segmentation in convoluted cancer spheroids via Bayesian optimization and deep-learning;2024-09-10

2. Advance in the application of organoids in bone diseases;Frontiers in Cell and Developmental Biology;2024-09-03

3. Production of marine-derived bioactive peptide molecules for industrial applications: A reverse engineering approach;Biotechnology Advances;2024-09

4. A Method to Study Migration and Invasion of Mouse Intestinal Organoids;Organoids;2024-08-21

5. Integrated nanoporous electroporation and sensing electrode array for total dynamic time-domain cardiomyocyte membrane resealing assessment;Bio-Design and Manufacturing;2024-08-20