Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with Gαi-Reference-Cited by-同舟云学术

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Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with Gαi

Published:1999-08 Issue:6747 Volume:400 Page:891-894
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Mochizuki Naoki,Ohba Yusuke,Kiyokawa Etsuko,Kurata Takeshi,Murakami Takeshi,Ozaki Takefumi,Kitabatake Akira,Nagashima Kazuo,Matsuda Michiyuki

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/23738.pdf

Reference25 articles.

1. Howe, L. R. & Marshall, C. J. Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1. J. Biol. Chem. 268, 20717–20720 (1993).

2. Alblas, J. et al. Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts. J. Biol. Chem. 268, 22235–22238 (1993).

3. Winitz, S. et al. Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J. Biol. Chem. 268, 19196–19199 (1993).

4. Crespo, P., Xu, N. Z., Simonds, W. F. & Gutkind, J. S. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits. Nature 369, 418–420 (1994).

5. Koch, W. J., Hawes, B. E., Allen, L. F. & Lefkowitz, R. J. Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G-βγ activation of p21ras. Proc. Natl Acad. Sci. USA 91, 12706–12710 (1994).

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