Enhancing the biocatalytic manufacture of the key intermediate of atorvastatin by focused directed evolution of halohydrin dehalogenase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep42064.pdf
Reference33 articles.
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2. Spelberg, J. H., Je, V. H. V., Tang, L., Janssen, D. B. & Kellogg, R. M. Highly enantioselective and regioselective biocatalytic azidolysis of aromatic epoxides. Organic Letters 3, 41–43 (2001).
3. Vries, E. J. D. & Janssen, D. B. Biocatalytic conversion of epoxides. Current Opinion in Biotechnology 14, 414–420 (2003).
4. Je, V. H. V. et al. Halohydrin dehalogenases are structurally and mechanistically related to short-chain dehydrogenases/reductases. Journal of Bacteriology 183, 5058–5066 (2001).
5. You, Z. Y., Liu, Z. Q. & Zheng, Y. G. Properties and biotechnological applications of halohydrin dehalogenases: current state and future perspectives. Applied Microbiology & Biotechnology 97, 9–21 (2013).
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