Development and evaluation of a high throughput inhalation model for organic chemicals

Author:

Linakis Matthew W.ORCID,Sayre Risa R.,Pearce Robert G.,Sfeir Mark A.,Sipes Nisha S.,Pangburn Heather A.,Gearhart Jeffery M.,Wambaugh John F.

Publisher

Springer Science and Business Media LLC

Subject

Public Health, Environmental and Occupational Health,Pollution,Toxicology,Epidemiology

Reference58 articles.

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2. National Toxicology Program. About NTP. https://ntp.niehs.nih.gov/about/index.html (2019). Accessed 21 Feb 2019.

3. Housenger J. Letter to stakeholders on EPA Office of Pesticide Programs’s Goal to Reduce Animal Testing from Jack E. Housenger, Director Office of Pesticide Programs. Regulations.gov—supporting & related material document. https://www.regulations.gov/document?D=EPA-HQ-OPP-2016-0093-0003. Accessed 21 Feb 2019.

4. Bessems JG, Loizou G, Krishnan K, Clewell HJ, Bernasconi C, Bois F, et al. PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA-EURL ECVAM ADME workshop. Regul Toxicol Pharmacol. 2014;68:119–39.

5. Boyes WK, Bercegeay M, Krantz T, Evans M, Benignus V, Simmons JE. Momentary brain concentration of trichloroethylene predicts the effects on rat visual function. Toxicol Sci J Soc Toxicol. 2005;87:187–96.

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