Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2009133.pdf
Reference54 articles.
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2. Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS . (2004). Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B. Cancer Res 64: 5212–5224.
3. Basile JR, Castilho RM, Williams VP, Gutkind JS . (2006). Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis. Proc Natl Acad Sci USA 103: 9017–9022.
4. Basile JR, Gavard J, Gutkind JS . (2007). Plexin-B1 utilizes RhoA and Rho kinase to promote the integrin-dependent activation of Akt and ERK and endothelial cell motility. J Biol Chem 282: 34888–34895.
5. Bielenberg DR, Hida Y, Shimizu A, Kaipainen A, Kreuter M, Kim CC et al. (2004). Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. J Clin Invest 114: 1260–1271.
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