The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2009296.pdf
Reference51 articles.
1. Ariga N, Sato E, Ohuchi N, Nagura H, Ohtani H . (2001). Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast. Int J Cancer 95: 67–72.
2. Bennett HL, Brummer T, Jeanes A, Yap AS, Daly RJ . (2007). Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis. Oncogene 27: 2693–2704.
3. Berrier AL, Yamada KM . (2007). Cell-matrix adhesion. J Cell Physiol 213: 565–573.
4. Bouscary D, Lecoq-Lafon C, Chretien S, Zompi S, Fichelson S, Muller O et al. (2001). Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo). Oncogene 20: 2197–2204.
5. Brummer T, Schramek D, Hayes VM, Bennett HL, Caldon CE, Musgrove EA et al. (2006). Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein. J Biol Chem 281: 626–637.
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