The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/ncb2254.pdf
Reference40 articles.
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3. Matthews, B. D., Overby, D. R., Mannix, R. & Ingber, D. E. Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J. Cell Sci. 119, 508–518 (2006).
4. Choquet, D., Felsenfeld, D. P. & Sheetz, M. P. Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 88, 39–48 (1997).
5. Zhao, X. H. et al. Force activates smooth muscle α-actin promoter activity through the Rho signalling pathway. J. Cell Sci. 120, 1801–1809 (2007).
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