Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility

Author:

Hai Rong,Schmolke Mirco,Leyva-Grado Victor H.,Thangavel Rajagowthamee R.,Margine Irina,Jaffe Eric L.,Krammer Florian,Solórzano Alicia,García-Sastre Adolfo,Palese Peter,Bouvier Nicole M.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Reference60 articles.

1. De Jong, M. D. et al. Oseltamivir resistance during treatment of influenza A (H5N1) infection. N. Engl. J. Med. 353, 2667–2672 (2005).

2. European Centre for Disease Prevention and Control (ECDC). ECDC/WHO frequently asked questions for Oseltamivir Resistance http://ecdc.europa.eu/en/healthtopics/seasonal_influenza/antivirals/pages/influenza_ antiviral_resistance_oseltamivir.aspx (2008).

3. Le, Q. M. et al. Avian flu: isolation of drug-resistant H5N1 virus. Nature 437, 1108 (2005).

4. World Health Organization (WHO). Overview of the emergence and characteristics of the avian influenza A(H7N9) virus http://www.who.int/influenza/human_animal_interface/influenza_h7n9/WHO_H7N9_ review_31May13.pdf (2013).

5. World Health Organization (WHO). Influenza at the human-animal interface: Summary and assessment as of 4 June 2013 http://www.who.int/influenza/human_animal_ interface/Influenza_Summary_IRA_HA_;interface_04Jun13.pdf; (2013).

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