A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates-Reference-Cited by-同舟云学术

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

Published:2013-12 Issue:1 Volume:4 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Tachmazidou Ioanna, ,Dedoussis George,Southam Lorraine,Farmaki Aliki-Eleni,Ritchie Graham R. S.,Xifara Dionysia K.,Matchan Angela,Hatzikotoulas Konstantinos,Rayner Nigel W.,Chen Yuan,Pollin Toni I.,O’Connell Jeffrey R.,Yerges-Armstrong Laura M.,Kiagiadaki Chrysoula,Panoutsopoulou Kalliope,Schwartzentruber Jeremy,Moutsianas Loukas,Tsafantakis Emmanouil,Tyler-Smith Chris,McVean Gil,Xue Yali,Zeggini Eleftheria

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms3872.pdf

Reference30 articles.

1. Peltonen, L., Palotie, A. & Lange, K. Use of population isolates for mapping complex traits. Nat. Rev. Genet. 1, 182–190 (2000).

2. Zeggini, E. Next-generation association studies for complex traits. Nat. Genet. 43, 287–288 (2011).

3. Pollin, T. I. et al. A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Science 322, 1702–1705 (2008).

4. Huyghe, J. R. et al. Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat. Genet. 45, 197–201 (2013).

5. Keys, A. Coronary Heart Disease in seven countries. Circulation 41, 1–211 (1970).

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