Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition-Reference-Cited by-同舟云学术

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition

Published:2013-11-26 Issue:1 Volume:4 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Anstee Quentin M.,Knapp Susanne,Maguire Edward P.,Hosie Alastair M.,Thomas Philip,Mortensen Martin,Bhome Rohan,Martinez Alonso,Walker Sophie E.,Dixon Claire I.,Ruparelia Kush,Montagnese Sara,Kuo Yu-Ting,Herlihy Amy,Bell Jimmy D.,Robinson Iain,Guerrini Irene,McQuillin Andrew,Fisher Elizabeth M.C.,Ungless Mark A.,Gurling Hugh M.D.,Morgan Marsha Y.,Brown Steve D.M.,Stephens David N.,Belelli Delia,Lambert Jeremy J.,Smart Trevor G.,Thomas Howard C.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms3816.pdf

Reference48 articles.

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2. Edenberg, H. J. et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am. J. Hum. Genet. 74, 705–714 (2004).

3. Enoch, M. A. The role of GABA(A) receptors in the development of alcoholism. Pharmacol. Biochem. Behav. 90, 95–104 (2008).

4. Parsian, A. & Zhang, Z. H. Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene. Am. J. Med. Genet. 88, 533–538 (1999).

5. Porjesz, B. et al. Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc. Natl Acad. Sci. USA 99, 3729–3733 (2002).

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