Regulation of B-cell fate by antigen-receptor signals
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri955.pdf
Reference154 articles.
1. Kitamura, D., Roes, J., Kuhn, R. & Rajewsky, K. A B-cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ-chain gene. Nature 350, 423–426 (1991).
2. Lam, K. P., Kuhn, R. & Rajewsky, K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90, 1073–1083 (1997). This paper shows the requirement for surface B-cell receptor (BCR) for the maintenance of mature B-cell subsets.
3. Meffre, E. & Nussenzweig, M. C. Deletion of immunoglobulin-β in developing B cells leads to cell death. Proc. Natl Acad. Sci. USA 99, 11334–11339 (2002). This paper proposes a requirement for surface BCR and signalling for immature B-cell survival.
4. Hardy, R. R. & Hayakawa, K. B-cell development pathways. Annu. Rev. Immunol. 19, 595–621 (2001).
5. Kurosaki, T. Genetic analysis of B-cell antigen receptor signaling. Annu. Rev. Immunol. 17, 555–592 (1999).
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