Mutant-selective topologic conversion facilitates selective degradation of a pathogenic prion isoform
Author:
Funder
The Autho
National Research Foundation of Korea
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41418-019-0354-1.pdf
Reference42 articles.
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2. Kim SJ, Rahbar R, Hegde RS. Combinatorial control of prion protein biogenesis by the signal sequence and transmembrane domain. J Biol Chem. 2001;276:26132–40.
3. Kim SJ, Hegde RS. Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel. Mol Biol cell. 2002;13:3775–86.
4. Prusiner SB. Prions. Proc Natl Acad Sci USA. 1998;95:13363–83.
5. Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, et al. A transmembrane form of the prion protein in neurodegenerative disease. Science. 1998;279:827–34.
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