A possible non-proteolytic role of ubiquitin conjugation in alleviating the pathology of Huntingtin’s aggregation-Reference-Cited by-同舟云学术

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A possible non-proteolytic role of ubiquitin conjugation in alleviating the pathology of Huntingtin’s aggregation

Published:2020-09-10 Issue:2 Volume:28 Page:814-817
ISSN:1350-9047
Container-title:Cell Death & Differentiation
language:en
Short-container-title:Cell Death Differ

Author:

Ziv Noam E.,Ciechanover Aaron

Funder

European Commission

Rappaport Foundation

Rappaport Family Institute for Biomedical Research Allen and Jewel Prince Center for Neurodegenerative Disorders of the Brain

German-Israeli Foundation for Scientific Research and Development

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41418-020-00617-7.pdf

Reference25 articles.

1. Ghosh R, Tabrizi SJ. Huntington disease. Handb Clin Neurol. 2018;147:255–78.

2. Vitet H, Brandt V, Saudou F. Traffic signaling: new functions of Huntingtin and axonal transport in neurological disease. Curr Opin Neurobiol. 2020;63:122–30.

3. Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell. 1996;87:493–506.

4. Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell. 1997;90:537–48.

5. Yang H, Yang S, Jing L, Huang L, Chen L, Zhao X, et al. Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form. Nat Commun. 2020;11:2582.

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1. Peripheral sequestration of huntingtin delays neuronal death and depends on N-terminal ubiquitination;Communications Biology;2024-08-18

2. Abnormal protein post-translational modifications induces aggregation and abnormal deposition of protein, mediating neurodegenerative diseases;Cell & Bioscience;2024-02-12

3. Peripheral sequestration of huntingtin delays neuronal death and depends on N-terminal ubiquitination;2023-11-09

4. Remote conditioning as protective strategy influencing ubiquitin-mediated stress response in the rabbit spinal cord after ischemia/reperfusion;General physiology and biophysics;2022

5. Emerging roles of the HECT-type E3 ubiquitin ligases in hematological malignancies;Discover Oncology;2021-10-08

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