RANK/OPG ratio of expression in primary clear-cell renal cell carcinoma is associated with bone metastasis and prognosis in patients treated with anti-VEGFR-TKIs

Author:

Beuselinck B,Jean-Baptiste J,Couchy G,Job S,De Reynies A,Wolter P,Théodore C,Gravis G,Rousseau B,Albiges L,Joniau S,Verkarre V,Lerut E,Patard J J,Schöffski P,Méjean A,Elaidi R,Oudard S,Zucman-Rossi J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference30 articles.

1. Beuselinck B, Job S, Becht E, Karadimou A, Verkarre V, Couchy G, Giraldo N, Rioux-Leclercq N, Molinié V, Sibony M, Elaidi R, Teghom C, Patard JJ, Méjean A, Fridman WH, Sautès-Fridman C, de Reyniès A, Oudard S, Zucman-Rossi J (2015) Molecular subtypes of clear cell renal cell carcinoma are associated to sunitinib response in the metastatic setting. Clin Cancer Res 6: 1329–1339.

2. Beuselinck B, Lerut E, Wolter P, Dumez H, Berkers J, Van Poppel H, Joniau S, Oyen R, De Wever L, Strijbos M, Paridaens R, Schöffski P (2014) Sarcomatoid dedifferentiation in metastatic clear cell renal cell carcinoma and outcome on treatment with anti-vascular endothelial growth factor receptor tyrosine kinase inhibitors: a retrospective analysis. Clin Genitourin Cancer 5: e205–e214.

3. Beuselinck B, Oudard S, Rixe O, Wolter P, Blesius A, Ayllon J, Elaidi R, Schöffski P, Barrascout E, Morel A, Escudier B, Lang H, Zucman-Rossi J, Medioni J (2011) Negative impact of bone metastasis on outcome in clear-cell renal cell carcinoma treated with sunitinib. Ann Oncol 4: 794–800.

4. Beuselinck B, Wolter P, Karadimou A, Elaidi R, Dumez H, Rogiers A, Van Cann T, Willems L, Body JJ, Berkers J, Van Poppel H, Lerut E, Debruyne P, Paridaens R, Schöffski P (2012) Concomitant oral tyrosine kinase inhibitors and bisphosphonates in advanced renal cell carcinoma with bone metastases. Br J Cancer 10: 1665–1671.

5. Broom RJ, Hinder V, Sharples K, Proctor J, Duffey S, Pollard S, Fong PC, Forgeson G, Harris DL, Jameson MB, O’Donnell A, North RT, Deva S, Hanning FJ, Grey A, Findlay MP (2014) Everolimus and zoledronic acid in patients with renal cell carcinoma with bone metastases: a randomized first-line phase ii trial. Clin Genitourin Cancer 1: 50–58.

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