The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog−driven medulloblastoma-Reference-Cited by-同舟云学术

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog−driven medulloblastoma

Published:2014-08-24 Issue:9 Volume:20 Page:1035-1042
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

He Xuelian,Zhang Liguo,Chen Ying,Remke Marc,Shih David,Lu Fanghui,Wang Haibo,Deng Yaqi,Yu Yang,Xia Yong,Wu Xiaochong,Ramaswamy Vijay,Hu Tom,Wang Fan,Zhou Wenhao,Burns Dennis K,Kim Se Hoon^ORCID,Kool Marcel,Pfister Stefan M,Weinstein Lee S,Pomeroy Scott L,Gilbertson Richard J,Rubin Joshua B,Hou Yiping,Wechsler-Reya Robert,Taylor Michael D,Lu Q Richard

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3666.pdf

Reference60 articles.

1. Taylor, M.D. et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 123, 465–472 (2012).

2. Northcott, P.A. et al. Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol. 122, 231–240 (2011).

3. Grammel, D. et al. Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem. Acta Neuropathol. 123, 601–614 (2012).

4. Sasai, K. et al. Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor. Cancer Res. 67, 3871–3877 (2007).

5. Kool, M. et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to Smoothened inhibition. Cancer Cell 25, 393–405 (2014).

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