GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

Author:

Thambyrajah Roshana,Mazan Milena,Patel Rahima,Moignard VictoriaORCID,Stefanska Monika,Marinopoulou Elli,Li Yaoyong,Lancrin ChristopheORCID,Clapes Thomas,Möröy Tarik,Robin Catherine,Miller Crispin,Cowley Shaun,Göttgens BertholdORCID,Kouskoff Valerie,Lacaud GeorgesORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Reference69 articles.

1. Costa, G., Kouskoff, V. & Lacaud, G. Origin of blood cells and HSC production in the embryo. Trends Immunol. 33, 215–223 (2012).

2. Palis, J., Robertson, S., Kennedy, M., Wall, C. & Keller, G. M. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 126, 5073–5084 (1999).

3. Frame, J. M., McGrath, K. E. & Palis, J. Erythro-myeloid progenitors: ‘definitive’ hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells. Blood Cells Mol. Dis. 51, 220–225 (2013).

4. McGrath, K. E. et al. Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo. Cell Rep. 11, 1892–1904 (2015).

5. Frame, J. M., Fegan, K. H., Conway, S. J., McGrath, K. E. & Palis, J. Definitive hematopoiesis in the yolk sac emerges from Wnt-responsive hemogenic endothelium independently of circulation and arterial identity. Stem Cells (2015)10.1002/stem.2213.

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