Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice-Reference-Cited by-同舟云学术

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Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

Published:2014-05-12 Issue:1 Volume:5 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Miwa Satomi,Jow Howsun,Baty Karen,Johnson Amy,Czapiewski Rafal,Saretzki Gabriele,Treumann Achim,von Zglinicki Thomas

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms4837.pdf

Reference69 articles.

1. Harman, D. The biologic clock: the mitochondria? J. Am. Geriatr. Soc. 20, 145–147 (1972).

2. Lapointe, J. & Hekimi, S. Early mitochondrial dysfunction in long-lived Mclk1+/− mice. J. Biol. Chem. 283, 26217–26227 (2008).

3. Lambert, A. J. et al. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms. Aging Cell 6, 607–618 (2007).

4. Pagliarini, D. J. et al. A mitochondrial protein compendium elucidates complex I disease biology. Cell 134, 112–123 (2008).

5. Kim, T. Y. et al. Metabolic labeling reveals proteome dynamics of mouse mitochondria. Mol. Cell. Proteomics 11, 1586–1594 (2012).

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