Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/28860.pdf
Reference30 articles.
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2. Bertoletti, A.et al. Cytotoxic T lymphocyte resonse to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. J. Exp. Med. 180, 933–943 (1994).
3. Pircher, H.et al. Viral escape by selection of cytotoxic T cell-resistant variants in vivo. Nature 346, 629–233 (1990).
4. Bertoletti, A.et al. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature 369, 407–410 (1994).
5. Klenerman, P.et al. Naturally occurring HIV-1 gag variants antagonize cytotoxic T-cell activity. Nature 369, 403–406 (1994).
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