Hurdles to the introduction of new therapies for immune-mediated kidney diseases
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nephrology
Link
http://www.nature.com/articles/nrneph.2015.206.pdf
Reference76 articles.
1. Machowska, A. et al. Therapeutics targeting persistent inflammation in chronic kidney disease. Transl. Res. 167, 204–213 (2015).
2. Weening, J. J. & Jennette, J. C. Historical milestones in renal pathology. Virchows Arch. 461, 3–11 (2012).
3. Trachtman, H. et al. A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis. Kidney Int. 79, 1236–1243 (2011).
4. Giglio, S. et al. Heterogeneous genetic alterations in sporadic nephrotic syndrome associate with resistance to immunosuppression. J. Am. Soc. Nephrol. 26, 230–236 (2015).
5. Sadowski, C. E. et al. A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. J. Am. Soc. Nephrol. 26, 1279–1289 (2015).
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