Azathioprine-related myelosuppression in a patient homozygous for TPMT*3A
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nephrology
Link
http://www.nature.com/articles/nrneph.2011.74.pdf
Reference30 articles.
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2. Relling, M. V. et al. Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin. Pharmacol. Ther. 89, 387–391 (2011).
3. Otterness, D. et al. Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms. Clin. Pharmacol. Ther. 62, 60–73 (1997).
4. Lennard, L., Van Loon, J. A., Lilleyman, J. S. & Weinshilboum, R. M. Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin. Pharmacol. Ther. 41, 18–25 (1987).
5. Sandborn, W. J. et al. Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease. North American Azathioprine Study Group. Gastroenterology 117, 527–535 (1999).
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