The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51-Reference-Cited by-同舟云学术

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The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51

Published:2016-05-13 Issue:10 Volume:23 Page:1579-1591
ISSN:1350-9047
Container-title:Cell Death & Differentiation
language:en
Short-container-title:Cell Death Differ

Author:

Antunica-Noguerol M,Budziñski M L,Druker J,Gassen N C,Sokn M C,Senin S,Aprile-Garcia F,Holsboer F,Rein T,Liberman A C,Arzt E

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/cdd201644.pdf

Reference60 articles.

1. de Kloet ER, Joels M, Holsboer F . Stress and the brain: from adaptation to disease. Nat Rev Neurosci 2005; 6: 463–475.

2. Binder EB . The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 2009; 34: S186–S195.

3. Cheung-Flynn J, Roberts PJ, Riggs DL, Smith DF . C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90. J Biol Chem 2003; 278: 17388–17394.

4. Sinars CR, Cheung-Flynn J, Rimerman RA, Scammell JG, Smith DF, Clardy J . Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes. Proc Natl Acad Sci USA 2003; 100: 868–873.

5. Wochnik GM, Ruegg J, Abel GA, Schmidt U, Holsboer F, Rein T . FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J Biol Chem 2005; 280: 4609–4616.

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1. SUMO regulation of FKBP51 activity and the stress response;Journal of Cellular Biochemistry;2023-04-26

2. Circadian glucocorticoids throughout development;Frontiers in Neuroscience;2023-04-25

3. Impact of Co-chaperones and Posttranslational Modifications Toward Hsp90 Drug Sensitivity;Subcellular Biochemistry;2022-12-16

4. Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity;Molecular Psychiatry;2022-03-08

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