Case histories, magic bullets and the state of drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2084.pdf
Reference43 articles.
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3. Kujubu, D. A., Fletcher, B. S., Varnuzu, B. C., Lim, R. W. & Herschmann, H. R. TISIO, a phorbol ester tumor promotor-inducible mRNA from Swiss 3T3 cells encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem. 266, 12866–12872 (1991).
4. Flower, R. J. & Vane, J. R. Selectivity of non-steroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl Acad. Sci. USA 90, 11693–11697 (1993).
5. Smith, W. L., DeWitt, D. L. & Garavito, R. M. Cyclooxygenases: structural and molecular biology. Am. Rev. Biochem. 69, 145–182 (2000).
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