Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation-Reference-Cited by-同舟云学术

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Complexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradation

Published:2013-01-13 Issue:2 Volume:20 Page:230-236
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Lapkouski Mikalai,Tian Lan,Miller Jennifer T,Le Grice Stuart F J,Yang Wei

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.2485.pdf

Reference62 articles.

1. Varmus, H. Reverse transcription. Sci. Am. 257, 56–59, 62–64 (1987).

2. Sarafianos, S.G. et al. Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. J. Mol. Biol. 385, 693–713 (2009).

3. Cihlar, T. & Ray, A.S. Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine. Antiviral Res. 85, 39–58 (2010).

4. de Béthune, M.P. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989–2009). Antiviral Res. 85, 75–90 (2010).

5. di Marzo Veronese, F. et al. Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. Science 231, 1289–1291 (1986).

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